Traveling long distances in cars with kids is in many ways like bathing a cat. It goes against their constitution, it's often a last resort, and you basically just hope to live through the experience with minimal scarring.
You can prepare for the young'uns entertainment with various tech-y items, art supplies, toys, and books. You pack snacks as though, instead of trekking through civilization, you're actually about to set sail to the New World. Throw in a couple of pillows and a blanket each, and if traveling with reasonable people, you might journey at least one town over before someone files a complaint about something.
There's got to be something in this for you. And since you totally can't drink and drive, I suggest comedy.
While I could compile hours and hours of hilarious bits of storytelling you could listen to when the kids fall asleep, there's no nap guarantee. Instead, I've rounded up some kid-safe gems you can fire up at any time.